Antibacterial Activity Test on Face Toner Preparations 70% Ethanol Extract of Avocado Leaves (Persea americana Mill) Against Staphylococcus Aureus Bacteria
DOI:
https://doi.org/10.56480/pratamamedika.v3i1.1195
Abstract View:
97
PDF downloads:
125
Keywords:
Facetoner, 70% Ethanol Extract, Avocado Leaves, Staphylococcus aureusAbstract
Improper use of antibiotics will cause resistance in bacteria so that other alternatives are needed such as the use of avocado plants as antibacterial plants. To determine the antibacterial activity of avocado leaf ethanol extract on the growth of Staphylococcus aureus bacteria. Laboratory experimental research to see the antibacterial activity of ethanol extract and avocado leaf fractions with concentrations of 15%, 20% and 25%. Antibacterial activity tests were carried out using the disk diffusion method against Staphylococcus aureus and comparing the inhibition zones formed from each treatment with the positive control, namely Tetracycline. The inhibition power obtained was then analyzed using the One Way Anova statistical method. The content of 70% avocado leaf ethanol extract compounds consists of flavonoids, saponins, tannins, alkaloids and terpenoids. Face toner preparation of 70% ethanol extract of avocado leaves F1 (15%) has 11.5mm, F2 (20%) has 15.7 mm and F3 (25%) has 21.4% antibacterial activity against the growth of Staphylococcus aureus bacteria. Formula 3 with a concentration of 25% with an inhibition zone of 21.4 mm has the most optimal antibacterial activity against Staphylococcus aureus bacteria. The most optimal avocado leaf face toner preparation as an antibacterial activity for Staphylococcus aureus is a concentration of 25%.
References
Aji, N. P. (2020). Uji Mutu Fisik Sediaan Toner yang Beredar di Kota Bengkulu. Jurnal Ilmiah Pharmacy, 7(2), 255–262. https://doi.org/10.52161/jiphar.v7i 2.192
Aprilia Rika Alvita. 2023. ‘Formulasi Sediaan Gel Ekstrak Daun Alpukat (Persea americana Mill) sebagai Terapi Pengobatan Luka Bakar Terhadap Kelinci New Seland White. Surakarta: Jurnal Medika Nusantara, https://doi.org/10.59680/medika.v1i4.628
Banu, R. H., Nagarajan, N. 2014, TLC and HPTLC fingerprinting of leaf extracts of Wedelia chinensis (Osbeck) Merrill, Journal of Pharmacognosy and Phytochemistry, 2(6), 29-33
Cempaka, R., Patmayuni, D., & Rendowaty, A. (2023). Ekstrak Etanol Daun Alpukat (Persea Americana Mill.) : Formulasi Krim dan Potensinya sebagai Anti Jerawat. Jurnal Ilmiah Bakti Farmasi, 1, 25–32.
Depkkes RL 2017. Farmakope herbal Indonesia. Edini II. Jakarta: Departemen
Kesehatan Republik Indonesia.
Draelos ZD. Novel topical therapies in cosmetic dermatology. Current Problems in Dermatology. 2019.
Endarini, L.H. 2016. Farmakognisi dan Fitokimia. Kementerian Kesehatan Republik Indonesia.
Ernawati dan K. Sari. 2015. Kandungan Senyawa Kimia dan Aktivitas Antibakteri Ekstrak Kulit Buah Alpukat (Persea Americana p.Mill) terhadap Bakteri Vibrio Alginolyticus. Jurnal Kajian Veteriner 3(2): 203-211.
Kementrian Kesehatan RI, 2017, Farmakope Herbal Indonesia, Edisi II, Kementrian Kesehatan Republik Indonesia, Jakarta.
Mardhiani, Y. D., Yulianti, H., Azhary, D., Rusdiana, T., Farmasetika, R. B., Farmasi, T., Tinggi, S., Bandung, F., & Soekarno-Hatta Bandung, J. (2017). FORMULASI DAN STABILITAS SEDIAAN SERUM DARI EKSTRAK KOPI HIJAU (Coffea canephora var. Robusta) SEBAGAI ANTIOKSIDAN. INDONESIA NATURAL RESEARCH PHARMACEUTICAL JOURNAL, 2(2), 19–33. https://doi.org/10.52447/INSPJ.V2 I2.910
Maulida, Z. (2020). Skrining Fitokimia Senyawa Metabolit Sekunder Ekstrak Etanol Daun Sambung Nyawa Gynura Procumbens (Blume) Miq. Karya Tulis Ilmiah. Bengkulu : Akademi Farmasi Al-Falah Yayasan Al Fathah.
Najib, A., Malik, A., Ahmad, A. R., Handayani, V., Syarif, R. A., & Waris, R. (2017). Standarisasi Ekstrak Air Daun Jati Belanda Dan Teh Hijau. Jurnal Fitofarmaka Indonesia, 4(2), 241–245. https://doi.org/10.33096/jffi.v4i2.268
Permatasari, R., Triswanto, S. 2015. Uji Aktivitas ekstrak Etanol Daun Alpukat (Persea Americana Mill) terhadap penyembuhan luka bakar pada punggung mencit jantan (Mus musculus). Jurnal Ilmiah Manuntung, 1(2), 100-106, 2015
Sari, R., & Ferdinan, A. (2017). Pengujian aktivitas antibakteri sabun cair dari ekstrak kulit daun lidah buaya. Pharmaceutical Sciences and Research, 4(3), 1.
Saifudin, A. 2014. Senyawa alam metabolit sekunder: teori, konsep dan teknik pemurnian. Deepublish, Yogyakarta.
Sanggrani, N. W. C. P. (2020). Bakteri S Taphylococcus Aureus. Skripsi Fakultas Kedokteran Universits Wijaya Kusuma Surabaya.
Sari, A. U., Annisa, N., Ibrahim, A., & Rijai, L. (2016). Uji Aktivitas Antibakteri Fraksi Daun Alpukat (Persea Americana Mill) Terhadap Bakteri Escherichia Coli Dan Staphylococcus Aureus. Prosiding Seminar Nasional Kefarmasian Ke-4, 20–21. https://doi.org/10.25026/mpc.v4i1.157
Sari, D. Y., Ariansyah, S., Shinta, S., & Beniardi, W. (2021). Face Tonic Formulation From Ethanol Extract of Maranta arundinacea L. With Variety of Cosolvent and Surfactant: Propylene Glycol and Polysorbate 80. 27th International Conference ADRI, 34-39. https://doi.org/10.26737/adri27
Sarinastiti. (2018). Perbandingan Efektivitas Ekstrak Daun Alpukat dan Biji Alpukat (Persea americana Mill) Sebagai Penghambat Pertumbuhan Bakteri Escherichia Coli dan Staphylococcus Aureus Secara In Vitro. Skripsi. Lampung : Universitas Islam Negeri Raden Intan Lampung.
Soemarie, Y. B., Astuti, T., & Rochmah, N. (2017). Formulasi Sediaan Salep
Ekstrak Etanol Daun Alpukat (Persea Americana Mill.) Sebagai Antiacne. Jurnal Ilmiah Manuntung, 2(2), 224–232. https://doi.org/10.51352/jim.v2i2.70
Sentat, Triswanto., Permatasari, Rizki. 2015. “Uji Aktivitas Ekstrak Etanol Daun Alpukat Terhadap Penyembuhan Luka Bakar pada Punggung Mencit Putih Jantan”. Jurnal Ilmiah Manutung. 1 (2).
Ummah K.K. (2022). Distribusi Metabolit Sekunder dan Aktivitas Antioksidan Biji Melinjo (Gnetum Gnemon L.) pada Tiga Tingkat Kematangan, Universitas Gajah Mada.
Yuska Novi Yanty, Densi Selpia Sopianti, Cindy Veronica, Fraksinasi Dan Skrining Fraksi Biji Kebiul (Caesalpinia bonduc (L) Roxb) Dengan Metode Ki (Kromatografi Lapis Tipis) Borneo Journal of Phamascientech, Vol. 113. No 01, Tahun 2019 ISSN-Print. 2541-3651 ISSN-Online, 2548-3897 Research Article.
Zeniusa, P. et al. (2019) ‘Uji Daya Hambat Ekstrak Etanol Teh Hijau Terhadap Escherichia coli Secara In Vitro’, Majority, 8(2), pp. 136–143.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Wendy Mayasari Kalalo, Wahyu Purwanjani , Supriyanto
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Copyright Notice
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-ShareAlike 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
