Test For Antioxidant Activity Of Hair Tonic Preparations Ethanol Extract 70% Pegagan Leaves (Centella asiatica (L.) Urban)
DOI:
https://doi.org/10.56480/pratamamedika.v3i1.1193
Abstract View:
55
PDF downloads:
71
Keywords:
Gotu Kola Leaves, Hair Tonic, AntioxidantAbstract
Gotu kola leaves (Centella asiatica (L.) Urban) are wild plants that grow in various places such as fields, plantations and in yards. Gotu kola leaves contain compounds such as polyphenols, β-carotene, tannins, vitamin C and saponins such as Madecassida and Asiaticoside. The asiaticoside found in gotu kola functions as an antioxidant that can capture free radicals. Objective: To determine the 70% ethanol extract of gotu kola leaves (Centella asiatica (L.) Urban) as a hair tonic as an antioxidant using different concentration variants. Method: This research is an experimental study by testing the antioxidant activity of a hair tonic preparation of gotu kola leaf extract (Centella asiatica (L.) Urban) in a hair tonic preparation on antioxidants using the DPPH 2,2 diphenyl-1-pikeylhydrazyl method. The 70% ethanol extract of gotu kola leaves was obtained using the maceration method with 70% ethanol solvent where the thick extract obtained was tested for its compound content. Then the extract with a concentration of 5ml, 10ml, 15ml was made into a hair tonic preparation after which it was tested for physical quality, organoleptic test, homogeneity test, pH test , viscosity test, specific gravity test. Vitamin C as a positive control and hair tonic base as a negative control. After obtaining comparisons, the data were processed statistically using ANOVA. Results: This research shows that the 70% ethanol extract of gotu kola leaves (Centella asiatica (L.) Urban) contains the chemical compounds triterpenoids, flavonoids, saponins, alkaloids and tannins. All hair tonic formulations have antioxidant activity based on the IC50 value. The statistical test results show that there is a significant difference in antioxidant activity, namely (p<0.05).
References
Amri et al, 2018. Pengaruh Kombinasi Ekstrak Buah Alpukat (Persea Americana Mill), Biji Pepaya (Carica Papaya L.), dan Daun Seledri (Apium raveolens L.) Terhadap Rambut dan Kulit Tikus (Rattus Novergicus). Hasanuddin Student Journal 2 (1): 180-188, Juni 2018.
Anggraini T, Diana S, Sahadi DI, Firdaus A. (2014). Pengaruh Penambahan Peppermint (Mentha piperita L.) Terhadap Kualitas Teh Daun Pegagan (Centella asiatica (L.) Urban). Jurnal Litbang Industri, Vol 4(2): Hal 79-88.
Anwar, S., Fitrianti, D. (2022). Hair Tonic dengan Kandungan Senyawa yang Memi. Journal Pharmacy, Vol. 2 No. 2, 1-4.
Arifin, A, A, A. (2021). FORMULASI dan MUTU FISIK SEDIAAN HAIR TONIC EKSTRAK BATANG PISANG KEPOK (Musa Balbisiana). [skripsi]. Malang: Akademi Analis Farmasi dan Makanan Putra Indonesia Malang.
Butar, Y. (2018). FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN SEDIAAN GEL EKSTRAK DAUN KEMANGI (Ocimum basilicus L.) DENGAN METODE DPPH SEBAGAI PENANGKAL RADIKAL BEBAS. Jakarta; Universitas Jakarta.
Hadi, H. P., Hilaliyati, N., Rahmi, A., &Si, M. (2023). Formulasi Dan Uji Fisik Sediaan Sabun Mandi Cair Dari Ekstrak Daun Pegagan (Centella asiatica (L) Urb) Kombinasi Minyak Lavender (Lavandula angustifolia). Pharmacy Science and Traditional Medicine Journal, 2(1), 107-115.
Hakim, A. R., & Saputri, R. (2020). Narrative Review: Optimasi Etanol sebagai Pelarut Senyawa Flavonoid dan Fenolik. Jurnal Surya Medika, 6(1), 177–180. https://doi.org/10.33084/jsm.v6i1.1641.
Hapsari, R. A., Wira, Y., Sy, C., & Konoralma, G. M. (2017). Pengaruh Air Rebusan Biji Alpukat Dan Daun Pandan Terhadap Kadar Gula Darah Penderita DM Tipe II Di Puskesmas Panarung Dan Bukit Hindu. Forum Kesehatan.
Harahap, Winda Hastuty. (2017). Formulasi Sediaan Krim Ekstrak Etanol Daun Nangka (Artocarpus Heterophyllus Lam.) Sebagai Anti-Aging. Medan: Universitas Sumatera Utara, Halaman 1.
Hasnaeni, Wisdawati, S. U. (2019). Pengaruh Metode Ekstraksi Terhadap Rendemen Dan Kadar Fenolik Ekstrak Tanaman Kayu Beta-Beta (Lunasia amara Blanco). Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal), 5(2), 166–174. https://doi.org/10.22487/j24428744.2019.v5.i2.13149.
Hidayah, R.N., Gozali, D., Hendriani, R. & Mustarichie, R. 2020. Formulasi dan Evaluasi Sediaan Herbal Hair tonic sebagai Perangsang Pertumbuhan Rambut. Majalah Farmasetika, 5 (5) : 218232. https://doi.org/10.21082/jp3.v35n3.p121-130.
Hidayat, T., & Suhendy, H. (2020). Formulasi Hair Tonic Ekstrak Kecambah Kacang Hijau Sebagai Hair Tonic. Journal of Pharmacopolium, 3(3), 152–156.
Jubaidah, S., Ria, I., Hayatus, S., Heri, W. (2018). FORMULASI DAN UJI PERTUMBUHAN RAMBUT KELINCI DARI SEDIAAN HAIR TONIC KOMBINASI EKSTRAK DAUN SELEDRI (Apium graveolens Linn) DAN DAUN MANGKOKAN (Polyscias scutellaria (Burm.f.) Fosberg). JURNAL ILMIAH MANUNTUNG, 4(1), 8-14.
Kementrian Kesehatan RI. (2017). Farmakope Herbal Indonesia Edisi II. Jakarta: Kementrian Kesehatan.
Lase, Yudita H. K. (2019). Formulasi Sediaan Hair Tonic Ekstrak Etanol Daun Waru (Hibiscus tileaceus L.) Digunakan Sebagai Penumbuh Rambut Pada Marmut (Cavia parcellus). [skripsi], Medan : Institut Kesehatan Helvetia Medan.
Manongko, P. S., Sangi, M. S., & Momuat, L. I. (2020). Uji Senyawa Fitokimia dan Aktivitas Antioksidan Tanaman Patah Tulang (Euphorbia tirucalli L.). Jurnal MIPA, 9(2), 64. https://doi.org/10.35799/jmuo.9.2.2020.28725.
Mulyanti Galih Dwi, Yuni Nurhayati, Ananda Ariska (2019). Uji Efek Formulasi Sediaan Hair Tonic Perasan Daun Kacang Panjang (Vigna Sinensis (L.) Savi Ex Hassk) Terhadap Pertumbuhan Rambut Kelinci Jantan. Wellness and Healthy Magazine, 1(2).
Putri, B. A., Sari, G. K., & Pistanty, M. A. (2023). Testing the Antibacterial Activity of A Serum Preparation Of Pegagan Leaf Extract (Centella Asiatica (L.) Urban) Against the Bacteria Propionibacterium Acnes. 2(1), 37-52.
Rahmawati, S., Mia, A., Putri, V, D. (2023). Formulasi Hair Tonic Ekstrak Bunga Telang (Clitoria Ternatea L.) Dan Aktivitas Antioksidan. Journal Of Social Science Research. Volume 3 Nomor 5.
Rizkayanti, Diah, A.W.M., & M. R. Jura. 2017. Uji Aktivitas Antioksidan Ekstrak Air Dan Ekstrak Etanol Daun Kelor (Moringa Oleifera LAM). Jurnal Akad. Kim 6. (2:125–131).
Rusdiana, I. (2018). Pengaruh Proporsi Ekstrak Lidah Buaya (Aloe vera) dan Madu Sebagai Bahan Aktif Hair Tonic. Jurnal Tata Rias, 7(2).
Rustiah, Waodeh., & Umriani, Nur. (2018). Uji Aktivitas Antioksidan dari Ekstrak Buah Kawista (Limonia acidissima L.) Menggunakan Spektrofotometer Uv-Vis. Jurnal Indo. J. Chem. Res., 6(1),22-25.
Setyawan, E. I., Padmanaba, I. G. P., Samirana, P. O. & Mahamuni, L. P. K. (2016). Efek PEG 400 dan mentol pada formulasi patch ekstrak daun sirih (Piper betle L.) terhadap pelepasan senyawa polifenol. Jurnal Farmasi Udayana. 5(2), pp. 12- 18.
Simangunsong, W. S. (2019). Formulasi Sediaan Masker Gel Dari Ekstrak Mentimun (Cucumis sativus L.) Kombinasi Ekstrak Buah Lemon (Citrus limon L.Burm.fil.). Karya Tulis Ilmiah Oleh, (Nurani 2012), 576–583.
Sumakno, A, H., Sari, P., Ahmad, A. B. (2021). Formulasi dan Uji Aktivitas Antioksidan Hair Tonic Ekstrak Daun Kunyit (Curcuma Domestica Val). Jurnal Ilmiah Farmasi.
Sumiati, T., Ferry, E., Eva, R. (2019). FORMULASI LOSION EKSTRAK HERBA PEGAGAN (Centella asiatica (L.)Urban) DAN UJI MUTU SERTA STABILITASNYA. Jurnal Farmamedika, 4(2), 62-69.
Sumiati, T., Ferry, E., Eva, R. (2019). FORMULASI LOSION EKSTRAK HERBA PEGAGAN (Centella asiatica (L.) Urban) DAN UJI MUTU SERTA STABILITASNYA. Jurnal Farmamedika, 4(2), 62-69.
Supriadi, Y. N. H. H. (2020). Formulasi Dan Evaluasi Fisik Sediaan Gel Rambut Ekstrak Etanol Daun Pare (Momordica Charantia L.) Dengan Konsentrasi Carbopol 940. 262–269, 262–269.
Yahya, M, A., Nurrosyidah, I, H. (2020). AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL HERBA PEGAGAN (Centella asiatica (L.) Urban) DENGAN METODE DPPH (2,2-Difenil-1-Pikrilhidrazil). Journal of Halal Product and Research (JHPR), Volume 3 Nomor 2, 106-112.
Yusran, Asriani I, Asri S. 2016. Bioaktiviras Ekstrak Metanol Daun Pegagan (Centella asiatica L.) Terhadap Pertumbuhan Bakteri Mycobacterium tuberculosis. Al-Kimia.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Lazaely Anggita Mayasari, Supriyanto, Estuningtyas Ayu Hapsari
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Copyright Notice
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-ShareAlike 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
