Uji Aktivitas Anti Aging Sediaan Gel Ekstrak Etanol 70 % Daun Salam (Syzygium polyanthum)
DOI:
https://doi.org/10.56480/pratamamedika.v3i1.1194
Abstract View:
168
PDF downloads:
218
Keywords:
Syzygium polyanthum, Gel, Stability, AcivityAbstract
Aging causes the skin to become wrinkled. The cause of aging is free radicals, free radicals in the form of UV-A rays. Bay leaf (Syzygium polyanthum) is a plant that contains flavonoid compounds which can act as antioxidants which can provide anti-aging activity. This test was carried out to find out that bay leaf extract gel was able to provide anti-aging activity. Methodology; The bay leaf extract was tested to be ethanol free and the chemical compound content was identified. The gel preparation was made using bay leaf extract with a concentration of 1.5%, 3%, 4.5%, which was tested for stability including organoleptic test, homogeneity test, pH test, adhesive test, viscosity test, and spreadability test and tested for anti-aging activity. includes percent collagen, percent elasticity, percent moisture.Results; The results of the FI, FII, and FIII gel stability tests meet the requirements for gel preparations including: pH test, viscosity test, adhesion test, and spreadability test. The results of testing the anti-aging activity of the bay leaf extract gel preparation with a concentration of 4.5% provided the most effective anti-aging effect. Conclusion; The results of the FI, FII, and FIII bay leaf extract gel tests had good stability. anti-aging activity test of bay leaf extract gel preparation with a concentration of 4.5% provided the most effective anti-aging effect.
References
Ardana, M., Aeyni, V., & Ibrahim, A. (2015). Formulasi dan optimasi basis gel HPMC (hidroxy propyl methyl cellulose) dengan berbagai variasi konsentrasi. Journal of Tropical Pharmacy and Chemistry, 3(2), 101-108.
Arnida, E. A. B., & Dini Rahmatika, S. (2021). Identifikasi Kandungan Senyawa Ekstrak Etanol Rimpang Purun Danau (Lepironia articulata (Retz.) Domin). In Prosiding Seminar Nasional Lingkungan Lahan Basah (Vol. 6, No. 2).
Fardin, F., & Adnan, J. (2022). POTENSI SEDIAAN SIRUP EKSTRAK DAUN SALAM (Syzygium Polyanthum) SEBAGAI KANDIDAT OBAT HERBAL TERSTANDAR DALAM MENURUNKAN KADAR ASAM URAT DARAH PADA MENCIT. Jurnal Farmasi Pelamonia/Journal Pharmacy Of Pelamonia, 2(2), 10-13
Kemenkes, R. I. (2017). Farmakope Herbal Indonesia Edisi II. Jakarta: Kementrian Kesehatan RI.
Putri, A. R., & Suhartinah, S. (2023). Uji Aktivitas Krim Anti-Aging Ekstrak Etanol Daun Bayam Merah (Amaranthus tricolor L.) pada Kulit Punggung Kelinci New Zealand yang dipapar Sinar UV-A. Indonesian Journal of Pharmaceutical Education, 3(1).
Popoola, O. K., Marnewick, J. L., Rautenbach, F., Ameer, F., Iwuoha, E. I., & Hussein, A. A. (2015). Inhibition of oxidative stress and skin aging-related enzymes by prenylated chalcones and other flavonoids from Helichrysum teretifolium. Molecules, 20(4), 7143-7155.
Rahman, N., Bahriul, P., & Diah, A. W. M. (2014). Uji aktivitas antioksidan ekstrak daun salam (Syzygium Polyanthum) dengan menggunanakan 1, 1-Difenil-2-Pikrilhidrazil. Jurnal Akademika Kimia, 3(3), 143-149.
Rihhadatulaisy, S., & Putriana, N. A. (2020). Aktivitas anti aging pada beberapa tanaman dengan berbagai metode pengujiannya. Farmaka, 18(1), 129-139.
Rinaldi, R., Fauziah, F., & Zakaria, N. (2021). Studi formulasi sediaan gel ekstrak etanol serai wangi (Cymbopogon nardus (L.) Randle) dengan basis HPMC. Jurnal Ilmiah Farmasi Simplisia (JIFS), 1(1), 33-42
Rosmayati, J., Wandira, A., Cindiansya, C., Anandari, R. F., Naurah, S. A., & Fikayuniar, L. (2023). Menganalisis Pengujian Kadar Air Dari Berbagai Simplisia Bahan Alam Menggunakan Metode Gravimetri. Jurnal Ilmiah Wahana Pendidikan, 9(17), 190-193.
Suryani, S. (2017). Formulasi Dan Uji Stabilitas Sediaan Gel Ekstrak Terpurifikasi Daun Paliasa (Kleinhovia Hospita L.) Yang Berefek Antioksidan. Pharmacon, 6(3).
Suryani, S. (2017). Formulasi Dan Uji Stabilitas Sediaan Gel Ekstrak Terpurifikasi Daun Paliasa (Kleinhovia Hospita L.) Yang Berefek Antioksidan. Pharmacon, 6(3).
Supriningrum, R., Sundu, R., Sentat, T., Niah, R., & Kumalasari, E. (2021). Karakterisasi Simplisia dan Ekstrak Kulit Batang Sekilang (Embelia borneensis Scheff.). Jurnal Ilmiah Ibnu Sina, 6(2), 196-205.
Tivani, I., Amananti, W., Putri, A. R., No, J. M., & Indonesia, K. T. J. T. (2021). Uji Aktivitas Antibakteri Handwash Ekstrak Daun Turi (Sesbania Grandiflora L) Terhadap Staphylococus Aureus. Jurnal Ilmiah Manuntung, 7(1), 86-91.
Wilapangga, A., & Sari, L. P. (2018). Analisis Fitokimia Dan Antioksidan Metode Dpph Ekstrak Metanol Daun Salam
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Anik Wahyuni, Wahyu Purwanjani , Supriyanto
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Copyright Notice
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-ShareAlike 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
