Formulation of Ethanol Extract Spray Gel Preparation of Sweet Starbumber Leaves (Averrhoa carambola L.)
DOI:
https://doi.org/10.56480/pratamamedika.v2i1.935Abstract View:
349PDF downloads:
351Keywords:
Averrhoa carambola L, Spray Gel, Physical StabilityAbstract
The sweet star fruit leaf plant (Averrhoa carambola L.) is a plant that has many benefits, one part of the plant that is often used is the leaves which contain alkaloids, flavonoids, saponins and tannins that can be made indo spray gel preparations. Spray gel or commonly called spray gel is a gel that has an aqueous phase of 10-90% of the weight of the spray preparation. This research aims to formulate a spray gel preparation of ethanol extract of sweet starfruit leaves (Averrhoa carambola L.) by testing the physical stability of the spray gel preparation. The formulation of spray gel preparations of sweet starfruit leaf extract (Averrhoa carambola L.) with concentrations of 0.1%, 1% and 1.5% was researched using laboratory experimental methods. Physical stability tests of spray gel preparations include organoleptic tests, pH tests, homogeneity tests, viscosity tests, spray pattern tests, dry time tests, cycling tests and centrifugation tests.The results of testing the physical stability of spray gel preparations for each formula fall within the range of requirements for spray gel preparations. To test the physical stability of the spray gel preparation after the cycling test, the viscosity test and pH test for each formula showed a decrease in each formula, while the organoleptic test did not show a significant change in each formula after the cycling test. The centrifugation test results for each formula showed that it was stable, indicated by the absence of syneresis or phase separation. Based on research, it was found that at the highest concentration the spray gel preparation of ethanol extract of sweet star fruit leaves (Averrhoa crambola L.) had a good physical stability test.
References
Abtian, M. S. (2019). Skrining Fitokimia Ekstrak Air Daun Belimbing Manis (Averrhoa carambola L.). Jurnal Mahasiswa Farmasi Fakultas Kedokteran UNTAN, 4 (1).
Aisyah, Isna Jati. 2019. “ Aktivitas Antibakteri Ekstrak Daun Suruhan (Peperomia Pellucida L. Kunth) Terhadap Bakteri Staphylococus Aureus.” Jurnal Farmasi Indonesia 16(2):98-105. Doi: 10.31001/Jfi.V16i2.494.
Alamsyah, Heru Kurniawan, Ita Widowati, and Agus Sabdono. 2014. “Agar Dari Perairan Pulau Panjang Jepara Terhadap Bakteri Escherichia Coli Dan Staphylococcus Epidermidis.” Journal of marine reserch 3:69-78.
Anindhita, MA, Oktaviani, N., & Pekalongan, U. (2020). Formulasi spray gel ekstrak daun pandan wangi sebagai antiseptik tangan. Ejournal Poltektegal , 9 (1), 14-21.
Banu, R. H., Nagarajan, N. 2014, TLC and HPTLC fingerprinting of leaf extracts of Wedelia chinensis (Osbeck) Merrill, Journal of Pharmacognosy and Phytochemistry, 2(6), 29-33.
Budi, A. S., Bachri, M.S., Maryanti, E., Ramdhan, M.A, Isgiyanto, A., (2020) Skrining Fitokimia Ekstrak Etanol Daun Jati dan Infusa Daun Jati (Tectona grandis L.S) dengan Metode Kromatografi Lapis Tipis (KLT)
Cendana Y, Adrianta KA, Suena NMDS. Formulasi Spray Gel Minyak Atsiri Kayu Cendana ( Santalum album L .) sebagai Salah Satu Kandidat Sediaan Anti Inflamasi. J Ilm Medicam. 2021;7(2):84-89.
Chasanah, U. (2017). ‘Uji Aktivitas Antioksidan Krim Ekstrak Green Tea dengan Fase Minyak VCP dan Minyak Zaitun dengan Metode DPPH’. Seminar Nasinal dan Gelar Produk. Malang: 17-18 Oktober 2017, pp. 137-141.
Estikomah SA, Sri A, Amal S, Safaatsih SF. Uji Daya Hambat Terhadap Bakteri Staphylococcus aureus, Staphylococcus epidermidis , Propionibacterium acnes Gel Semprot Ekstrak Etanol Daun Kersen ( Muntingia calabura L .) Karbopol 940. Pharmacon J Ilm Farm.2021;5(1):36-53.
Fitriansyah SN, Wirya S, Cici H. Formulasi dan Evaluasi Spray Gel Fraksi Etil Asetat Pucuk Daun Teh Hijau (Camelia sinensis [L.] Kuntze) Sebagai Antijerawat. Pharmacy. 2016;13(2):2016.
Hanani, E. (2014) Analisis Fitokimia. Penerbit buku kedokteran ECG. Jakarta.
Hayati R, Sari A, Chairunnisa C. Formulasi Spray Gel Ekstrak Etil Asetat Bunga Melati (Jasminum sambac (L.) Ait.) Sebagai Antijerawat. Indones J Pharm Nat Prod. 2019;2(2):5964. doi:10.35473/ijpnp.v2i2.256
Kementerian Kesehatan Ri. 2017. Farmakope Herbal Indonesia Edisi ii.
Mindawarnis, dan A. Jariah. (2019). ‘Mutu Ekstrak Etanol Daun Encok (Plumbago zeylanica L.) berdasarkan Perbedaan Waktu Pengambilan Simplisia’. Jurnal Kesehatan Pharmasi, 1 (1), pp. 1-10. doi: 10.36086/jpharm.v1i1
Muthu, N., Lee, S. Y., Phua, K. K., dan Bhore, S. J. 2016. Nutritional, medicinal and toxicological attributes of Star-Fruits (Averrhoa carambola L.): A Review. Bioinformation 12(12):420-424.
Nafisah, M, Tukiran, S., & Hidayati, N. (2014). Uji skrining fitokimia pada ekstrak heksan, kloroform dan metanol dari tanaman patikan kebo (Euphorbiae hirtae). In Prosiding seminar nasional kimia (pp. 279-286).
Nawangsari D, Sunarti. Uji Stabilitas Sediaan Salep Ekstrak Etanol Rimpang Kencur (Kaempferiae galanga L.) dalam Berbagai Basis. J Pharmacopolium. 2021;4(2):67-74.
Novia, D. (2020). Skrining Fitokimia Ekstrak Etanol Daun Jati Dan Infusa Daun Jati (Tectona grandis LS) Dengan Metode Kromatografi Lapis Tipis (KLT). Jurnal Ilmiah Pharmacy, 7(2), 159-174.
Pujiastuti A, Kristiani M. Formulasi dan Uji Stabilitas Mekanik Hand and Body Lotion Sari Buah Tomat (Licopersicon esculentum Mill.) sebagai Antioksidan. J Farm Indones. 2019;16(1):42-55
Puspita W, Puspasari H, Restanti NA. Formulasi Dan Pengujian Sifat Fisik Sediaan Spray Gel Ekstrak Etanol Daun Buas-Buas (Premna Serratifolia L.). J Ilm Farm Bahari. 2020;11(2):145.
Rasyadi Y, Zaunit M, Safitri R. Formulasi dan Karakterisasi Spray Gel Hand Sanitizer Ekstrak Etil Asetat Daun Kunyit (Curcuma domestica Val). J Farm Higea. 2021;13(2):2021.
Rukmini, A., Utomo, D. H., & Laily, A. N. (2019, September). Skrining Fitokimia Familia Piperaceae. In Prosiding Seminar Nasional Hayati (Vol. 7, pp. 6-12).
Salwa S, Abd Kadir M Bin, Sulistyowati Y. Formulasi Dan Evaluasi Sediaan Spray Gel Tabir Surya Fraksi Etil Asetat Daun Cempedak (Artocarpus integer (Thunb.) Merr.) Dengan Kombinasi Basis Hpmc Dan Karbopol 940. J Mhs Kesehat. 2020;2(1):12-23.
Sari, B. L., Noviardi, H., & Kartini, N. A. (2017). Optimasi Waktu Maserasi Parasetamol Dalam Jamu Pegal Linu Yang Beredar Di Bogor Barat. Jurnal Farmamedika (Pharmamedika Journal), 2(1), 17-29.
Simo, A., Naiome Kawal, G. Paliyath, M. Bakovic. (2014) ‘Botanical Antioxidants for Skin Health in the World of Cosmeceuticals’. International Journal of Advanced Nutritional and Health Science, 2 (1), pp. 67-88. doi : 10.23953/CLOUD.IJANHS.153.
Zubaydah, W. Z. W., Novianti, R., & Indalifiany, A. (2022). Pengembangan dan pengujian sifat fisik sediaan spray gel darı ekstrak etanol batang Etlıngera rubroloba menggunakan basıs gel Na-CMC. Journal Borneo, 2(2), 38-49.
Downloads
Published
Issue
Section
License
Copyright (c) 2023 Eka Ammyta Putri Perdanti, Gigih Kenanga Sari, Maulita Saraswati
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Copyright Notice
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-ShareAlike 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.