Uji Aktivitas Antibakteri Serum Ekstrak Etanol 70% Daun Turi Putih (Sesbania grandiflora L) Terhadap Bakteri Staphylococcus Aureus
DOI:
https://doi.org/10.56480/pratamamedika.v3i1.1192
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White turi leaves, Extract, Serum, Staphylococcus aureus.Abstrak
White turi is a plant that contains active substances that act as antibacterials, including saponins, flavonoids and tannins which can inhibit the growth of Staphylococcus aureus bacteria. Currently, the use of natural ingredients in cosmetic preparations has been developed. One of the cosmetic preparations that has developed recently is serum. This study aims to determine the antibacterial activity of serum 70% ethanol extract of white turi leaves (Sesbania grandiflora L) against Staphylococcus aureus bacteria. This research method is experimental research. White turi leaves were extracted using the maceration method with 70% ethanol solvent. The 70% ethanol extract of white turi leaves was made into serum with a concentration of 2%, 4%, 8% and the physical quality was evaluated including organoleptic tests, homogeneity, pH, spreadability, viscosity and the antibacterial activity of the serum was tested using the paper disk diffusion method. The results of the research on the formulation of the serum preparation are brownish yellow in color, have a distinctive odor of 70% ethanol extract of white turi leaves and are slightly thick, homogeneous, with a pH value = 5.65-5.86, spreadability = 5.3-6.33, viscosity = 341.66-466.46 and the inhibition zone for antibacterial activity of formula 1 is 9.48 mm (medium), formula 2 is 12.50 mm (strong) and formula 3 is 14.46 mm (strong). Based on the results obtained, it can be concluded that all serum formulas of 70% ethanol extract of white turi leaves can inhibit the growth of Staphylococcus aureus bacteria in the medium-strong category and the serum formula of 70% ethanol extract of white turi leaves (Sesbania grandiflora L) has the best activity on growth. Staphylococcus aureus bacteria is formula 3 with a concentration of 8% with an inhibition zone of 14.46 mm (strong).
Referensi
Amalia, R., Marfu'ah, N., & Amal, S. (2018). Aktivitas antibakteri kayu siwak (salvadora persica) fraksi eter terhadap bakteri staphylococcus aureus secara in vitro. Pharmasipha: Pharmaceutical Journal of Islamic Pharmacy, 2(1), 16-21.
Amira, K. J. (2021). Formulasi Sediaan Serum Dari Ekstrak Buah Belimbing Wuluh (Averrhoa bilimbi L.) Terhadap Bakteri Propionibacterium acnes Secara In Vitro (Doctoral dissertation, Stikes Karya Putra Bangsa Tulungagung.
Anggarini, D., Raharjeng, S. W., Safitri, C. I. N. H., & Pangestuti, Z. (2021, October). Formulasi dan Evaluasi Serum Anti Jerawat Berbasis Minyak Atsiri (Curcuma zedoaria). In Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek) (pp. 406-415).
Aulia, R. (2019). Formulasi Krim Tipe M/A Ekstrak Etanol Daun Matoa (Pometia pinnata JR Frost & G. Forst.) Dan Uji Aktivitas Antibakteri Terhadap Staphylococcus aureus. Doctoral dissertation, Universitas Perintis Indonesia.
Djoko, W., Taurhesia, S., Djamil, R., & Simanjuntak, P. (2020). Standardisasi Ekstrak Etanol Herba Pegagan (Centella asiatica). Sainstech Farma: Jurnal Ilmu Kefarmasian, 13(2), 118-123.
Farhamzah, F., Khoerunnisa, A., & Wahyuningsih, E. S. (2024). Formulasi Dan Uji Aktivitas Antioksidan Sediaan Serum Ekstrak Etanol Biji Kopi Hijau (Coffea canephora pierre). Journal of Pharmacopolium, 6(2).
Farmakope Herbal Indonesia. (2017). Edisi II. Kementerian Kesehatan Republik Indonesia.
Fatimah, S., Prasetyaningsih, Y., & Astuti, R. W. (2022). Efektifitas Antibakteri Ekstrak Daun Pegagan (Centella Asiatica) Terhadap Pertumbuhan Bakteri Staphylococcus aureus. Lumbung Farmasi: Jurnal Ilmu Kefarmasian, 3(1), 61-68.
Fikayuniar, L., Kusumawati, A. H., Silpia, M. P., Monafita, H., & Tusyaadah, L. (2021). Formulasi Dan Uji Efektivitas Antibakteri Sediaan Serum Antijerawat Ekstrak Etanol Daun Kemangi (Ocimum x africanum Lour.). Jurnal Buana Farma, 1(4), 14-20.
Firmansyah, F., Khairiati, R., Muhtadi, W. K., & Chabib, L. (2022). Uji Aktivitas Antibakteri Serum Ekstrak Etanol Buah Belimbing Wuluh Terhadap Propionibacterium acnes, Staphylococcus aureus, dan Staphylococcus epidermis. Majalah Farmasi dan Farmakologi, 26(2), 69-73.
Hasrawati, A., Hardianti, H., Qama, A., & Wais, M. (2020). Pengembangan Ekstrak Etanol Limbah Biji Pepaya (Carica papaya L.) Sebagai Serum Antijerawat. Jurnal Fitofarmaka Indonesia, 7(1), 1-8.
Hasrawati, A., Hardianti, H., Qama, A., & Wais, M. (2020). Pengembangan Ekstrak Etanol Limbah Biji Pepaya (Carica papaya L.) Sebagai Serum Antijerawat. Jurnal Fitofarmaka Indonesia, 7(1), 1-8.
Hidayah, H., Kusumawati, A. H., Sahevtiyani, S., & Amal, S. (2021). Literature Review Article: Aktivitas Antioksidan Formulasi Serum Wajah Dari Berbagai Tanaman. Journal of Pharmacopolium, 4(2).
Hidayat, F., Komarudin, D., Ekadipta, E., & Lestari, Y. P. (2022). Formulasi Masker Gel Peel-Off Dari Ekstrak Bunga Turi (Sesbania grandiflora (L.) Pers). ISTA Online Technologi Journal, 3(2), 53-61.
Iien, H., Zulkifli, L., & Sedijani, P. (2020). Aktivitas Antibakteri Ekstrak Metanol Daun Turi (Sesbania grandiflora L.) Terhadap Pertumbuhan Klebsiella pneumoniae. Jurnal Biologi Tropis, 20(2), 219-226.
Indrawati, A., Isnaeni, D., Baharuddin, S., & Luthfiah, N. (2022). Efektivitas Ekstrak Etanol Daun Turi (Sesbania grandiflora (L.) Pers.) Terhadap Pertumbuhan Pseudomonas aeruginosa dan Staphylococcus aureus. Lumbung Farmasi: Jurnal Ilmu Kefarmasian, 3(2), 231-240.
Julianti, P. A., Hutahaen, T. A., & Februyani, N. (2023). Formulasi sediaan gel antiacne ekstrak daun sirih (Piper betle L.) sebagai alternatif terapi acne vulgaris terhadap bakteri Propionibacterium acnes secara in vitro. Indonesian Journal of Health Science, 3(2), 308-319.
Kabakoran, J. F., Niwele, A., & Yuyun, M. (2022). Uji Aktivitas Antibakteri Ekstrak Etanol Daun Turi (Sesbania Grandiflora L) Terhadap Pertumbuhan Stapylococcus Aureus Dengan Metode Cakram. Jurnal Ilmiah Kedokteran dan Kesehatan, 1(2), 126-141.
Nurleni, N., Firdiawan, A., Salsabila, A., & Amelia, K. (2023). Formulasi Sediaan Serum Asam Kojat Dengan Variasi Gliserin Sebagai Enhancer Dan Evaluasi Stabilitas Fisika Waktu Sebenarnya. Innovative: Journal Of Social Science Research, 3(1), 611-617.
Rasyidi, R. D. G., Noviany., A. Nurfidayat dan A. Setianingrum. (2015). Skrining Fitokimia dan Uji Klt Ekstrak Metanol Beberapa Tumbuhan Yang Berpotensi Sebagai Obat Tradisional Di Lampung. Seminar Nasional Sains dan Teknologi VI. Halaman 685-695.
Ratnah, S., Rahim, A. R., & Hasyim, H. (2018). Aktivitas Antimikroba Ekstrak Daun Turi Putih (Sesbania Grandiflora L.) Terhadap Pertumbuhan Candida Albicans dan Staphylococcus Aureus. Media Farmasi, 14(1), 17- 21.
Rosmayanti, D. A., Raharjeng, S. W., & Safitri, C. I. N. H. (2021). Formulasi Dan Stabilitas Mutu Fisik Serum Minyak Atsiri Kayu Manis (Cinnamomum burmannii) Sebagai Anti Jerawat. In Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek) (pp. 512-517).
Sambode, Y. C., Simbala, H., & Rumondor, E. (2022). Penentuan Skrining Fitokimia, Parameter Spesifik Dan Non Spesifik Ekstrak Umbi Bawang Hutan (Eleutherine americana Merr). PHARMACON, 11(2), 1389-1394.
Sandei Mutia. (2022). Uji Aktivitas Antijamur Krim Ekstrak Daun Turi Putih (Serbania grandiflora L.) Variasi Konsentrasi Setil Alkohol Sebagai Stiffening Agent Terhadap Jamur Candida albicans. Skripsi. Universitas Setia Budi, Surakarta.
Sari, D. E. M. (2023). Uji Aktivitas Sediaan Gel Handsanitizer dari Ekstrak Etanol Daun Turi Putih (Sesbania grandiflora L) terhadap Bakteri Staphylococcus Aureus. Jurnal Ilmiah Pharmacy, 10(1), 72-80.
Savitri, E., Fakhrurrazi, F., Harris, A., Erina, E., Sutriana, A., & Lubis, T. M. (2018). Uji Antibakteri Ekstrak Daun Kelor (Moringa oleifera L.) Terhadap Pertumbuhan Bakteri Staphylococcus aureus (Antibacterial Activity Test of Moringa oleifera L. Extracts on Staphylococcus aureus). Jurnal Ilmiah Mahasiswa Veteriner, 2(3), 373-379.
Sony, D. (2021). Formulasi Gel Ekstrak Etanol Daun Binahong (Anredera cordifolia (Ten) Steenis) Dan Uji Aktivitas Antibakteri Terhadap Staphylococcus epidermidis. Doctoral dissertation, Universitas Perintis Indonesia.
Tivani, I., Amananti, W., Putri, A. R., No, J. M., & Indonesia, K. T. J. T. (2021). Uji Aktivitas Antibakteri Handwash Ekstrak Daun Turi (Sesbania Grandiflora L) Terhadap Staphylococus Aureus. Jurnal Ilmiah Manuntung, 7(1), 86-91.
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